Does previous abdominal surgery alter the outcome of pediatric patients subjected to orthotopic liver transplantation?

Cuervas-Mons, V and Rimola, A and Van Thiel, DH and Gavaler, JS and Schade, RR and Starzl, TE (1986) Does previous abdominal surgery alter the outcome of pediatric patients subjected to orthotopic liver transplantation? Gastroenterology, 90 (4). 853 - 857. ISSN 0016-5085

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Abstract

The medical, anesthesia, and surgical records of 89 consecutive pediatric patients who underwent an orthotopic hepatic transplantation procedure at the University of Pittsburgh from February 1981 to May 1984 were reviewed to evaluate the effect of prior abdominal surgery upon the morbidity and mortality of orthotopic liver transplantation in children. Fifty-seven children (group 1) had had prior abdominal surgery, whereas 32 (group 2) had not. The group 1 subjects were younger (p < 0.001), had better prothrombin times (p < 0.01), and better platelet counts (p < 0.02) than did those in group 2. No difference in the duration of anesthesia or intraoperative use of fresh frozen plasma or platelets was evident between the two groups. However, group 1 patients were given more red blood cells intraoperatively than were the group 2 patients (p < 0.01). The group 1 patients had more total postoperative infections (p < 0.05), which was due solely to a greater number of abdominal infections (p < 0.05), but similar total hospital and intensive care unit stays as did the group 2 patients. When those in group 1 were divided into those having a previous Kasai procedure versus those who did not, no differences between the two groups were apparent except for age. Based upon these data, we conclude that prior abdominal surgery does not affect mortality, the duration of hospital or intensive care unit stay, plasma or platelet requirements, and total anesthesia time required for orthotopic liver transplantation, but does enhance the number of red blood cell transfusions and infections, particularly abdominal infections, in children undergoing this procedure. © 1986.

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Details

Item Type:	Article
Status:	Published
Creators/Authors:	Creators Email Pitt Username ORCID Cuervas-Mons, V Rimola, A Van Thiel, DH Gavaler, JS Schade, RR Starzl, TE tes11@pitt.edu TES11
Centers:	Other Centers, Institutes, Offices, or Units > Thomas E. Starzl Transplantation Institute
Date:	1 January 1986
Date Type:	Publication
Journal or Publication Title:	Gastroenterology
Volume:	90
Number:	4
Page Range:	853 - 857
DOI or Unique Handle:	10.1016/0016-5085(86)90860-7
Institution:	University of Pittsburgh
Refereed:	Yes
ISSN:	0016-5085
Other ID:	uls-drl:31735062119643, Starzl CV No. 678
Date Deposited:	08 Apr 2010 17:11
Last Modified:	02 Feb 2019 13:55
URI:	http://d-scholarship.pitt.edu/id/eprint/4064

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