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Representing Genes: Classical Mapping Techniques and the Growth of Genetical Knowledge

Weber, Marcel (1998) Representing Genes: Classical Mapping Techniques and the Growth of Genetical Knowledge. Studies in History and Philosophy of Biological and Biomedical Sciences, 29 (2). pp. 295-315. ISSN 1369-8486

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Abstract

Classical genetics and its relation to molecular biology have been subject to extensive philosophical discussion. Most of the debate so far has been focused on the question
of whether classical or “transmission” genetics has been reduced, in some sense, to molecular biology. This question was motivated by a notion inherited from logical empiricist philosophy of science, namely that the growth of scientific knowledge consists in (derivational) reduction of statements from the precincts of an older (but mature) theory by those of a more advanced theory. However, no consensus has been
reached on where exactly on a reduction-replacement scale the case of genetics should be located. I do not wish to add another one to the long list of elaborate arguments
advanced on this problem. Instead, I shall try to open a new perspective on the growth of genetical knowledge by examining the role of classical gene mapping techniques.


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Item Type: Published Article or Volume
Creators:
CreatorsEmailORCID
Weber, Marcelmarcel.weber@unige.ch
Keywords: Classical genetics, molecular biology, reduction, structure, colinearity, mapping
Subjects: Specific Sciences > Biology > Molecular Biology/Genetics
General Issues > Experimentation
General Issues > Reductionism/Holism
General Issues > Structure of Theories
Depositing User: Prof. Marcel Weber
Date Deposited: 12 Jan 2023 17:41
Last Modified: 12 Jan 2023 17:41
Item ID: 21645
Journal or Publication Title: Studies in History and Philosophy of Biological and Biomedical Sciences
Publisher: Elsevier
Official URL: https://www.sciencedirect.com/science/article/abs/...
DOI or Unique Handle: https://doi.org/10.1016/S1369-8486(98)00017-X
Subjects: Specific Sciences > Biology > Molecular Biology/Genetics
General Issues > Experimentation
General Issues > Reductionism/Holism
General Issues > Structure of Theories
Date: 1998
Page Range: pp. 295-315
Volume: 29
Number: 2
ISSN: 1369-8486
URI: https://philsci-archive-dev.library.pitt.edu/id/eprint/21645

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