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Against Evidentiary Pluralism in Pharmaceutical Regulation

Sung, Richard and Holman, Bennett (2022) Against Evidentiary Pluralism in Pharmaceutical Regulation. In: UNSPECIFIED.

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Abstract

We examine arguments for and against the use of mechanistic evidence in assessing treatment efficacy and find that advocates of EBM+ and their critics have largely been talking past each other due to difference in focus. We explore aducanumab for the treatment of Alzheimer’s disease as a case which may (eventually) speak to the role of EBM+ in pharmaceutical regulation. The case suggests the debate may be more fruitful if philosophers confine debates to particular domains of medical science and weigh in prospectively instead of relying on historical cases where outcomes are known and which are susceptible to hindsight bias.


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Item Type: Conference or Workshop Item (UNSPECIFIED)
Creators:
CreatorsEmailORCID
Sung, Richardrcdsung@gmail.com0000-0001-8779-6256
Holman, Bennettbholman@yonsei.ac.kr0000-0001-9038-2644
Keywords: EBM+, clinical trials, drug regulation, commercialization
Subjects: General Issues > Evidence
Specific Sciences > Medicine
General Issues > Social Epistemology of Science
General Issues > Values In Science
Depositing User: Mr. Richard Sung
Date Deposited: 12 Jul 2022 03:53
Last Modified: 12 Jul 2022 03:53
Item ID: 20874
Subjects: General Issues > Evidence
Specific Sciences > Medicine
General Issues > Social Epistemology of Science
General Issues > Values In Science
Date: 2022
URI: https://philsci-archive-dev.library.pitt.edu/id/eprint/20874

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