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Has classical gene position been practically reduced?

Vidal, Oriol and Teira, David (2020) Has classical gene position been practically reduced? Biology & Philosophy. ISSN 1572-8404

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Abstract

One of the defining features of the classical gene was its position (a band in the chromosome). In molecular genetics, positions are defined instead as nucleotide numbers and there is no clear correspondence with its classical counterpart. However, the classical gene position did not simply disappear with the development of the molecular approach, but survived in the lab associated to different genetic practices. The survival of classical gene position would illustrate Waters’ view about the practical persistence of the genetic approach beyond reductionism and anti-reductionist claims. We show instead that at the level of laboratory practices there are also reductive processes, operating through the rise and fall of different techniques. Molecular markers made the concept of classical gene position practically dispensable, leading us to rethink whether it had any causal role or was just a mere heuristic


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Item Type: Published Article or Volume
Creators:
CreatorsEmailORCID
Vidal, Oriol
Teira, David0000-0002-4551-2371
Additional Information: Accepted in Biology and Philosophy
Keywords: gene, position, reductionism, practice
Subjects: Specific Sciences > Biology > Molecular Biology/Genetics
General Issues > Causation
General Issues > Reductionism/Holism
Depositing User: Prof. David Teira
Date Deposited: 30 Jan 2022 05:06
Last Modified: 13 Dec 2023 16:28
Item ID: 20162
Journal or Publication Title: Biology & Philosophy
Publisher: Springer
Official URL: https://link.springer.com/article/10.1007%2Fs10539...
DOI or Unique Handle: https://doi.org/10.1007/s10539-020-09767-x
Subjects: Specific Sciences > Biology > Molecular Biology/Genetics
General Issues > Causation
General Issues > Reductionism/Holism
Date: 2020
ISSN: 1572-8404
URI: https://philsci-archive-dev.library.pitt.edu/id/eprint/20162

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