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A Pre-Birth Guide to Personhood: How Genetic, Epigenetic and Developmental Milieu Factors Influence Pre-Fertilization, Embryonic, Fetal and Neonatal Attributes of Future Individual Humans

Hughes, Claude and Hughes, Gavin (2021) A Pre-Birth Guide to Personhood: How Genetic, Epigenetic and Developmental Milieu Factors Influence Pre-Fertilization, Embryonic, Fetal and Neonatal Attributes of Future Individual Humans. [Preprint]

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Hughes and Hughes Pre Birth Guide to Personhood How Genetic Epigenetic and Developmental Milieu Factors Influence Pre-Fertilization Embryonic Fetal and Neonatal Attributes of Future Individual Humans 06 OCT 2021.pdf

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Abstract

Discrete events and processes influence development of individual future humans. While we do not wish to redefine personhood, we relate a newly discovered epigenetic
event to sources of individuality of future humans. Genetic and epigenetic events and developmental milieu processes diversify developmental trajectories of future individual
humans prior to societal entry via parturition. First, fertilization and epigenetic resetting of each individual’s organismic clock to time zero (t=0) at day 15 of embryogenesis, are two discrete discreet biological events that impact a future individual human’s attributes.
Second, those two discrete discreet biological events are immersed in the continuous developmental process spanning pre-fertilization and gestation, further driving
individualization of diverse attributes of each future human before the discrete blatant biological event of parturition (birth) and societal entry. Exposures of the gravida to
multiple diverse exogenous exposures means that morphogenesis and physiogenesis of every embryo/fetus has individualized attributes for its future human lifespan.


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Item Type: Preprint
Creators:
CreatorsEmailORCID
Hughes, Claudeclhughes@duke.edu0000-0001-5178-2258
Hughes, Gavingavinch@email.unc.edu
Keywords: personhood, epigenetics, biological organismic clock, physiogenesis, potential human, future human
Subjects: Specific Sciences > Medicine > Biomedical Ethics
General Issues > Ethical Issues
General Issues > Laws of Nature
General Issues > Science and Society
Depositing User: Dr Claude Hughes
Date Deposited: 31 Oct 2021 23:41
Last Modified: 31 Oct 2021 23:41
Item ID: 19771
Subjects: Specific Sciences > Medicine > Biomedical Ethics
General Issues > Ethical Issues
General Issues > Laws of Nature
General Issues > Science and Society
Date: 29 October 2021
URI: https://philsci-archive-dev.library.pitt.edu/id/eprint/19771

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