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Immune-Mediated Repair: A Matter of Plasticity

Laurent, Paôline and Jolivel, Valérie and Manicki, Pauline and Chiu, Lynn and Contin-Bordes, Cécile and Truchetet, Marie-Elise and Pradeu, Thomas (2017) Immune-Mediated Repair: A Matter of Plasticity. Frontiers in Immunology, 8. ISSN 1664-3224


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Though the immune system is generally defined as a system of defense, it is increasingly
recognized that the immune system also plays a crucial role in tissue repair and its potential dysregulations. In this review, we explore how distinct immune cell types are involved
in tissue repair and how they interact in a process that is tightly regulated both spatially
and temporally. We insist on the concept of immune cell plasticity which, in recent years,
has proved fundamental for the success/understanding of the repair process. Overall,
the perspective presented here suggests that the immune system plays a central role in
the physiological robustness of the organism, and that cell plasticity contributes to the
realization of this robustness.

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Item Type: Published Article or Volume
Laurent, Paôline
Jolivel, Valérie
Manicki, Pauline
Chiu, Lynn
Contin-Bordes, Cécile
Truchetet, Marie-Elise
Pradeu, Thomas
Depositing User: Thomas Pradeu
Date Deposited: 18 Oct 2020 02:46
Last Modified: 18 Oct 2020 02:46
Item ID: 18262
Journal or Publication Title: Frontiers in Immunology
Official URL:
DOI or Unique Handle:
Date: 2017
Volume: 8
ISSN: 1664-3224

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