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What Makes a Discovery Successful? The Story of Linda Buck and the Olfactory Receptors

Barwich, Ann-Sophie (2020) What Makes a Discovery Successful? The Story of Linda Buck and the Olfactory Receptors. Cell, 181 (4). pp. 749-753.

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Abstract

In 1991, Buck and Axel published a landmark study in Cell for work that was awarded the 2004 Nobel Prize. The identification of the olfactory receptors as the largest family of GPCRs catapulted olfaction into mainstream neurobiology. This BenchMark revisits Buck’s experimental innovation and its surprising success at the time.


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Item Type: Published Article or Volume
Creators:
CreatorsEmailORCID
Barwich, Ann-Sophieabarwich@iu.edu0000-0003-0123-9366
Keywords: Olfaction, neuroscience, oral history, biochemistry, molecular biology, genetics, scientific discovery, methodology, tools, narrative
Subjects: Specific Sciences > Biology > Molecular Biology/Genetics
General Issues > Experimentation
General Issues > History of Philosophy of Science
Specific Sciences > Neuroscience > Molecular Neuroscience
Depositing User: Dr. Ann-Sophie Barwich
Date Deposited: 15 May 2020 03:36
Last Modified: 15 May 2020 03:36
Item ID: 17181
Journal or Publication Title: Cell
Official URL: https://www.cell.com/cell/fulltext/S0092-8674(20)3...
DOI or Unique Handle: https://doi.org/10.1016/j.cell.2020.04.040
Subjects: Specific Sciences > Biology > Molecular Biology/Genetics
General Issues > Experimentation
General Issues > History of Philosophy of Science
Specific Sciences > Neuroscience > Molecular Neuroscience
Date: 14 May 2020
Page Range: pp. 749-753
Volume: 181
Number: 4
URI: https://philsci-archive-dev.library.pitt.edu/id/eprint/17181

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