PhilSci Archive

Binding Specificity and Causal Selection in Drug Design

Lean, Oliver M (2019) Binding Specificity and Causal Selection in Drug Design. [Preprint]

This is the latest version of this item.

[img]
Preview
Text
Lean, O.M. (Forthcoming) Binding Specificity and Causal Selection in Drug Design (preprint).pdf

Download (348kB) | Preview

Abstract

Binding specificity is a centrally important concept in molecular biology, yet it has received little philosophical attention. Here I aim to remedy this by analyzing binding specificity as a causal property. I focus on the concept’s role in drug design, where it is highly prized and hence directly studied: From a causal perspective, understanding why binding specificity is a valuable property of drugs contributes to an understanding of causal selectionーof how and why scientists distinguish between causes, not just causes from non-causes. In particular, the specificity of drugs is precisely what underwrites their value as experimental interventions on biological processes.


Export/Citation: EndNote | BibTeX | Dublin Core | ASCII/Text Citation (Chicago) | HTML Citation | OpenURL
Social Networking:
Share |

Item Type: Preprint
Creators:
CreatorsEmailORCID
Lean, Oliver Momlean@gmail.com
Additional Information: Forthcoming in "Philosophy of Science"
Keywords: causation; causality; causal selection; molecular biology; specificity; drug design; intervention
Subjects: Specific Sciences > Biology > Molecular Biology/Genetics
General Issues > Causation
General Issues > Evidence
General Issues > Technology
Depositing User: Dr. Oliver Lean
Date Deposited: 07 Aug 2019 13:44
Last Modified: 07 Aug 2019 13:44
Item ID: 16314
Subjects: Specific Sciences > Biology > Molecular Biology/Genetics
General Issues > Causation
General Issues > Evidence
General Issues > Technology
Date: 2019
URI: https://philsci-archive-dev.library.pitt.edu/id/eprint/16314

Available Versions of this Item

Monthly Views for the past 3 years

Monthly Downloads for the past 3 years

Plum Analytics

Actions (login required)

View Item View Item