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Some Liked It Hot: A Hypothesis Regarding Establishment of the Proto-Mitochondrial Endosymbiont During Eukaryogenesis

Dunn, Cory D. (2017) Some Liked It Hot: A Hypothesis Regarding Establishment of the Proto-Mitochondrial Endosymbiont During Eukaryogenesis. Journal of Molecular Evolution, 85. pp. 99-106.

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Abstract

Eukaryotic cells are characterized by a considerable increase in subcellular
compartmentalization when compared to prokaryotes. Most evidence suggests that
the earliest eukaryotes consisted of mitochondria derived from an
α-proteobacterial ancestor enclosed within an archaeal host cell. However, what
benefits the archaeal host and the proto-mitochondrial endosymbiont might have
obtained at the beginning of this endosymbiotic relationship remains unclear. In
this work, I argue that heat generated by the proto-mitochondrion initially
permitted an archaeon living at high temperatures to colonize a cooler
environment, thereby removing apparent limitations on cellular complexity.
Furthermore, heat generation by the endosymbiont would have provided phenotypic
flexibility not available through fixed alleles selected for fitness at specific
temperatures. Finally, a role for heat production by the proto-mitochondrion
bridges a conceptual gap between initial endosymbiont entry to the archaeal host
and a later role for mitochondrial ATP production in permitting increased
cellular complexity.


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Item Type: Published Article or Volume
Creators:
CreatorsEmailORCID
Dunn, Cory D.cory.dunn@helsinki.fi0000-0003-2393-5944
Keywords: endosymbiosis, eukaryogenesis, mitochondria, archaea, temperature
Subjects: Specific Sciences > Biology > Evolutionary Theory
Specific Sciences > Biology > Molecular Biology/Genetics
Specific Sciences > Biology > Systematics
Depositing User: Dr. Cory Dunn
Date Deposited: 14 Nov 2017 15:50
Last Modified: 14 Nov 2017 15:50
Item ID: 13441
Journal or Publication Title: Journal of Molecular Evolution
Publisher: Springer
Official URL: http://link.springer.com/article/10.1007/s00239-01...
DOI or Unique Handle: https://doi.org/10.1007/s00239-017-9809-5
Subjects: Specific Sciences > Biology > Evolutionary Theory
Specific Sciences > Biology > Molecular Biology/Genetics
Specific Sciences > Biology > Systematics
Date: 14 July 2017
Page Range: pp. 99-106
Volume: 85
URI: https://philsci-archive-dev.library.pitt.edu/id/eprint/13441

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