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Synthetic Modeling and Mechanistic Account: Material Recombination and Beyond

Knuuttila, Tarja and Loettgers, Andrea (2012) Synthetic Modeling and Mechanistic Account: Material Recombination and Beyond. In: UNSPECIFIED.

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Abstract

Recently, Bechtel and Abrahamsen have argued that mathematical models study the dynamics of mechanisms by recomposing the components and their operations into an appropriately organized system. We will study this claim through the practice of combinational modeling in circadian clock research. In combinational modeling experiments on model organisms and mathematical/computational models are combined with a new type of model—a synthetic model. While we appreciate Bechtel and Abrahamsen’s point that mathematical/computational models are used to provide dynamic mechanistic explanations, we think that the strategy of recomposition is more complicated than what Bechtel and Abrahamsen indicate. Moreover, as we will show, synthetic modeling as a kind of material recomposition strategy also points beyond the mechanistic paradigm.


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Item Type: Conference or Workshop Item (UNSPECIFIED)
Creators:
CreatorsEmailORCID
Knuuttila, Tarjatarja.knuuttila@helsinki.fi
Loettgers, Andrealoettger@caltech.edu
Keywords: Dynamic mechanistic explanations, mathematical models, synthetic models, genetic circuits, noise, modularity, integration
Subjects: Specific Sciences > Biology > Molecular Biology/Genetics
General Issues > Experimentation
General Issues > Explanation
General Issues > Models and Idealization
Depositing User: Tarja Tellervo Knuuttila
Date Deposited: 15 May 2013 21:06
Last Modified: 15 May 2013 21:06
Item ID: 9764
Subjects: Specific Sciences > Biology > Molecular Biology/Genetics
General Issues > Experimentation
General Issues > Explanation
General Issues > Models and Idealization
Date: October 2012
URI: https://philsci-archive-dev.library.pitt.edu/id/eprint/9764

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